h�bbd``b`��@�� H��쿀g��n�&�dM��5 q�#�Z�#��_ �� Azathioprine should take effect after several doses, but its full effect may take several weeks. Do not give this medication to breeding or pregnant pets. Mild interactions of azathioprine include: This information does not contain all possible interactions or adverse effects. Pet owners should wear gloves when giving this medication and wash hands afterwards. Azathioprine needs to be tapered off over several months according to your veterinarian's directions. Azathioprine is excreted at low levels in. The usual dose of azathioprine can vary and is dependent on the type of condition being treated. Contact your veterinarian if you notice fever, reduced activity, bruising, bleeding, vomiting, lack of appetite, or yellowing of the whites of eyes, gums, or skin (jaundice). This medicine usually comes in the form of 50 mg tablets scored down the middle for easy splitting. See additional information. You may have more of a chance of getting an infection. Azathioprine should not be stopped suddenly in animals who have been taking it, as their immune systems are likely to overreact and cause the disease or disorder to start again. Can you supply this liquid form instead of the 50 MG pills? Do not take 2 doses at the same time or extra doses. x��]k�� 5��`"���F ��`�����tw���q��(n�8 R��}�n|�ib�D�[)q�J̕�}%��b�z���I�n��/���0MA���q.��]�4���v�^6m>�E�v%{��8��i���0���+z��F�x�s͆i�a��lj��Ϻ�5�ؑ�F�k!����[�9��Q�8�u����-��Z� mu��%o��o/n�߀f�6k)�ԣW>��ʆ����=�� Take after meals unless your doctor says otherwise. /Title (��) Please enable JavaScript in order to continue using our website. Chronic immunosuppression with this purine antimetabolite increases neoplasia risk, mutagenic risk, and hematologic toxicities. Drugs other than those listed may also interact with azathioprine. Azathioprine SAFETY DATA SHEET Supersedes Revision: 04/25/2018 P264: Wash {hands} thoroughly after handling. What Is Azathioprine and How Does It Work? progressive multifocal leukoencephalopathy, Pianist With RA Finds Another Path to Music, 3-5 mg/kg/day intravenously/orally initially on day of transplant or 3 days before transplant (rare), Maintenance: 1-3 mg/kg/day intravenously/orally, 1 mg/kg/day intravenously/orally initially, Maintenance: Reduce daily dose by 0.5 mg/kg every 4 weeks until lowest effective dosage is reached, Adult: 2 mg/kg/day orally with or without low-dose corticosteroids, Children under 12 years: Safety and efficacy not established, Children over 12 years: 2 mg/kg/day orally with or without low-dose corticosteroids, Maintenance, remission, or reduction of steroid, 1-2 mg/kg orally once daily to maximum daily dose of 150 mg for at least 3-6 months before typical response is observed, Lower dosage (100 mg/day) is reported effective in some patients, Longer treatment duration (up to 84 months) is reported in some patients, 1 mg/kg/day intravenously/orally initially in single daily dose or divided every 12 hours; may be increased by 0.5 mg/kg/day after 6-8 weeks, then by 0.5 mg/kg/day every 4 weeks; not to exceed 2.5 mg/kg/day, Administration concomitantly with or within 14 days of, Pheochromocytoma: Serious reactions, including elevated, See "What Are Side Effects Associated with Using Azathioprine?". 41 0 obj <>/Filter/FlateDecode/ID[<1E85EDDE91E1C81EAF7BB8CB5A39E376><063EF40AA5289541B5AB8E240A3172E9>]/Index[30 25]/Info 29 0 R/Length 70/Prev 26782/Root 31 0 R/Size 55/Type/XRef/W[1 2 1]>>stream Azathioprine has moderate interactions with at least 42different drugs. /ColorSpace /DeviceGray Long-term use may raise your chance of cancer. doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. Do not share your drugs with others and do not take anyone else's drugs. P362+364: Take off contaminated clothing and wash it before … The veteran should be acknowledged with the vitamin supplements the pet is taking. Azathioprine is an immunosuppressive antimetabolite that lowers the body's immune system used to prevent the body from rejecting a transplanted kidney.Azathioprine is also used to treat symptoms of rheumatoid arthritis.. Azathioprine is available under the following different brand names: Azasan, and Imuran.